Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 3/20 | 0.44 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13416055 | 0.85 | KDM4E (0.53) | ADRA1DADRA1AADRA1BMEN1KMT2A | |
| SCHEMBL13416048 | 0.82 | PROKR1 (0.47) | ADRA1ASLC6A2SLC6A4DRD2DRD3 | |
| SCHEMBL1837165 | 0.80 | GRM2 (0.51) | MEN1KMT2ACYP3A4GAAKDM4E | |
| Hydrochloric Acid SCHEMBL1835586 | 0.79 | GRM2 (0.50) | MEN1KMT2ACYP3A4GAAKDM4E | |
| SCHEMBL26284674 | 0.79 | ADRA1D (0.43) | ADRA1DADRA1AADRA1BMEN1KMT2A | |
| SCHEMBL21787709 | 0.77 | MEN1 (0.51) | ADRA1DADRA1AADRA1BMEN1KMT2A | |
| SCHEMBL18022528 | 0.77 | MEN1 (0.51) | ADRA1DADRA1AADRA1BMEN1KMT2A | |
| SCHEMBL15834214 | 0.77 | HTR2C (0.52) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24877620 | 0.77 | SLC6A2 (0.47) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16110654 | 0.76 | KDM1A (0.59) | ADRA1DADRA1AADRA1BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283425-A1 | ARYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT MODULATE IKZF2 | Plexium, Inc. (US) | 2023-01-12 | — | — | WO | disclosed |