Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24519848 | 0.84 | KDM4E (0.54) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20861913 | 0.81 | IKBKB (0.53) | SLC6A2SLC6A4TSHRHTR2AHTR2C | |
| SCHEMBL24877635 | 0.80 | TSHR (0.42) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL824172 | 0.79 | QDPR (0.53) | THPO | |
| SCHEMBL15834214 | 0.78 | HTR2C (0.52) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL31473580 | 0.77 | LMNA (0.42) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL13369611 | 0.77 | CHRNB4 (0.48) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL21787691 | 0.77 | CHRNB4 (0.48) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL13807402 | 0.77 | CHRNB4 (0.48) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL24877487 | 0.77 | ADRA1D (0.46) | SLC6A2SLC6A4SLC6A3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283425-A1 | ARYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT MODULATE IKZF2 | Plexium, Inc. (US) | 2023-01-12 | — | — | WO | disclosed |