Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467878 | 0.81 | CA2 (0.55) | — | |
| SCHEMBL28830799 | 0.79 | ENPP2 (0.47) | ENPP2PTGS2EPHX1AKR1C3EPHX2 | |
| SCHEMBL1428902 | 0.78 | ENPP2 (0.48) | ENPP2PTGS2AKR1C3KCNJ1KCNH2 | |
| SCHEMBL10453221 | 0.76 | ENPP2 (0.42) | ENPP2PTGS2AKR1C3DAO | |
| SCHEMBL10453222 | 0.76 | ENPP2 (0.42) | ENPP2PTGS2AKR1C3DAO | |
| SCHEMBL10453223 | 0.76 | ENPP2 (0.42) | ENPP2PTGS2AKR1C3DAO | |
| SCHEMBL27730326 | 0.75 | ENPP2 (0.45) | ENPP2PTGS2EPHX1AKR1C3GRIN2B | |
| SCHEMBL31591064 | 0.74 | IDO1 (0.45) | ALDH1A1CYP1A2 | |
| SCHEMBL28533247 | 0.74 | IDO1 (0.45) | ALDH1A1CYP1A2 | |
| SCHEMBL3671622 | 0.74 | IDO1 (0.45) | ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108822135-B | Synthesis method of nitrogen heterocyclic ring substituted thieno [3, 2-d ] thiazole and derivatives thereof | 湘潭大学 | 2021-02-02 | — | — | CN | claimed |
| EP-2379542-A1 | NOVEL OXIME DERIVATIVES | Cadila Healthcare Limited (IN) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010084512-A1 | NOVEL OXIME DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2010-07-29 | — | — | WO | disclosed |
| WO-2009125434-A2 | OXIME DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2009-10-15 | — | — | WO | disclosed |