SCHEMBL28830799

SCHEMBL28830799

CS(=O)(=O)c1ccc(C/C=C/O)cc1

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 2/20 0.47
PTGS2 P35354 3/20 0.42
AKR1C3 P42330 2/20 0.41
EPHX2 P34913 1/20 0.39
NR1H4 Q96RI1 1/20 0.39
DAO P14920 1/20 0.39
TGM2 P21980 1/20 0.39
EPHX1 P07099 1/20 0.38
GSR P00390 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10453222 0.81 ENPP2 (0.42) ENPP2PTGS2AKR1C3DAO
SCHEMBL10453223 0.81 ENPP2 (0.42) ENPP2PTGS2AKR1C3DAO
SCHEMBL10453221 0.81 ENPP2 (0.42) ENPP2PTGS2AKR1C3DAO
SCHEMBL1428902 0.79 ENPP2 (0.48) ENPP2PTGS2AKR1C3EPHX2NR1H4
SCHEMBL2487876 0.79 ENPP2 (0.45) ENPP2PTGS2AKR1C3EPHX2NR1H4
SCHEMBL28347902 0.78 ENPP2 (0.39) ENPP2PTGS2AKR1C3DAO
SCHEMBL27730326 0.76 ENPP2 (0.45) ENPP2PTGS2AKR1C3DAOEPHX1
SCHEMBL1750419 0.73 ENPP2 (0.50) ENPP2PTGS2EPHX2NR1H4DAO
SCHEMBL28478078 0.73 AGXT (0.43)
SCHEMBL96651 0.73 PTGS2 (0.68) ENPP2PTGS2EPHX2NR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957086-B Synthesis method and application of N-trifluoromethyl sulfonyl phthalimide 杭州师范大学 2023-06-02 CN disclosed
CN-114957086-A Synthesis method and application of N-trifluoromethylsulfonyl phthalimide 杭州师范大学 2022-08-30 CN disclosed