SCHEMBL24879009

SCHEMBL24879009

C=Cc1cnc(C(C)C)nc1NC

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACVR2A P27037 1/20 0.33
TGFBR1 P36897 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25469726 0.82
SCHEMBL3139494 0.74 ALDH1A1 (0.44) ACVR2ATGFBR1
SCHEMBL25523664 0.71 TRIM58 (0.34) ACVR2ATGFBR1
SCHEMBL15785397 0.71 LMNA (0.40) ACVR2ATGFBR1
SCHEMBL23774065 0.70 PDE10A (0.34) ACVR2ATGFBR1
SCHEMBL23978969 0.69
SCHEMBL23507843 0.68 CYP3A4 (0.42) ACVR2ATGFBR1
SCHEMBL22645170 0.68
SCHEMBL24879350 0.67
SCHEMBL22255221 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023282702-A1 SHP2 INHIBITOR AND USE THEREOF 주식회사 카나프테라퓨틱스 2023-01-12 WO disclosed