Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14950200 | 0.86 | TOP2A (0.48) | KDM4EALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL1457271 | 0.84 | KDM4E (0.45) | KDM4EALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL5800900 | 0.83 | TOP2A (0.47) | KDM4EALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL7637380 | 0.83 | KDM4E (0.44) | KDM4EALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL8571971 | 0.82 | KDM4E (0.43) | KDM4EALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL1457334 | 0.80 | TOP2A (0.45) | KDM4EALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL1456618 | 0.79 | BCHE (0.46) | KDM4EALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL7643118 | 0.76 | MEN1 (0.42) | KDM4EALDH1A1RAB9ASMN1; SMN2POLB | |
| SCHEMBL1457309 | 0.74 | ACP1 (0.37) | KDM4EALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL24879684 | 0.74 | POLB (0.40) | KDM4EALDH1A1RAB9ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230008368-A1 | IMIDAZOQUINOLINE SUBSTITUTED PHOSPHORIC ESTER AGONIST, AND PREPARATION THEREFOR AND APPLICATION THEREOF | SUZHOU ZELGEN BIOPHARMACEUTICALS CO., LTD. (CN) | 2023-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230008368-A1 | IMIDAZOQUINOLINE SUBSTITUTED PHOSPHORIC ESTER AGONIST, AND PREPARATION THEREFOR AND APPLICATION THEREOF | TLR4, TLR7, TLR1 | KDM4E 2733/4885ALDH1A1 2873/4885RAB9A 3624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.