Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14950200 | 0.90 | TOP2A (0.48) | TOP2AKDM4EPOLBGLAALDH1A1 | |
| SCHEMBL1456618 | 0.88 | BCHE (0.46) | TOP2AKDM4EPOLBGLAALDH1A1 | |
| SCHEMBL1457271 | 0.84 | KDM4E (0.45) | TOP2AKDM4EPOLBGLAALDH1A1 | |
| SCHEMBL1457334 | 0.84 | TOP2A (0.45) | TOP2AKDM4EPOLBGLAALDH1A1 | |
| SCHEMBL24879683 | 0.83 | KDM4E (0.44) | TOP2AKDM4EPOLBGLAALDH1A1 | |
| SCHEMBL7637380 | 0.83 | KDM4E (0.44) | TOP2AKDM4EPOLBGLAALDH1A1 | |
| SCHEMBL8571971 | 0.82 | KDM4E (0.43) | TOP2AKDM4EPOLBGLAALDH1A1 | |
| SCHEMBL20766797 | 0.77 | GAA (0.47) | TOP2AKDM4EPOLBGLAALDH1A1 | |
| SCHEMBL31709349 | 0.76 | ALDH1A1 (0.38) | ALDH1A1RAB9ABCHEACHEKMT2A | |
| SCHEMBL1457309 | 0.76 | ACP1 (0.37) | TOP2AKDM4EPOLBALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006065280-A2 | ISOXAZOLE, DIHYDROISOXAZOLE, AND OXADIAZOLE SUBSTITUTED IMIDAZO RING COMPOUNDS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-06-22 | — | — | WO | disclosed |