Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24879876 | 0.84 | ALDH1A1 (0.39) | ALDH1A1PPM1BPTPN1PPP1CCTSHR | |
| SCHEMBL24879307 | 0.83 | PPM1B (0.30) | PPM1BPTPN1PPP1CC | |
| SCHEMBL19032664 | 0.80 | CYP4F2 (0.43) | KMT2AALDH1A1MEN1L3MBTL1PPM1B | |
| SCHEMBL24879359 | 0.77 | GRM2 (0.31) | KMT2AMEN1 | |
| SCHEMBL24879374 | 0.74 | — | — | |
| SCHEMBL3954190 | 0.72 | PPM1B (0.44) | KMT2AALDH1A1NPSR1PPM1BPTPN1 | |
| SCHEMBL1027647 | 0.72 | PPM1B (0.44) | KMT2AALDH1A1NPSR1PPM1BPTPN1 | |
| SCHEMBL3954185 | 0.72 | PPM1B (0.44) | KMT2AALDH1A1NPSR1PPM1BPTPN1 | |
| SCHEMBL23533397 | 0.72 | ALDH1A1 (0.46) | KMT2AALDH1A1MEN1L3MBTL1PPM1B | |
| SCHEMBL19032508 | 0.70 | MAPT (0.44) | KMT2AALDH1A1L3MBTL1PPM1BPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023281040-A1 | STRAINED BI-FUNCTIONALIZED TRANS-CYCLOOCTENES | STICHTING RADBOUD UNIVERSITEIT (NL) | 2023-01-12 | — | — | WO | disclosed |