Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | PPM1B | O75688 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24879307 | 0.85 | PPM1B (0.30) | PPM1BPTPN1PPP1CC | |
| SCHEMBL24879890 | 0.84 | KMT2A (0.36) | ALDH1A1TSHRPPM1BPTPN1PPP1CC | |
| SCHEMBL24879374 | 0.79 | — | — | |
| SCHEMBL23533397 | 0.69 | ALDH1A1 (0.46) | ALDH1A1LMNAPPM1BPTPN1PPP1CC | |
| SCHEMBL2838452 | 0.68 | — | — | |
| SCHEMBL19032664 | 0.67 | CYP4F2 (0.43) | ALDH1A1LMNAHSD17B10PPM1BPTPN1 | |
| SCHEMBL19032508 | 0.67 | MAPT (0.44) | ALDH1A1LMNAHSD17B10TSHRPPM1B | |
| SCHEMBL19040832 | 0.66 | CES2 (0.40) | ALDH1A1TSHRPPM1BPTPN1PPP1CC | |
| SCHEMBL3954185 | 0.66 | PPM1B (0.44) | ALDH1A1LMNAHSD17B10PPM1BPTPN1 | |
| SCHEMBL3954190 | 0.66 | PPM1B (0.44) | ALDH1A1LMNAHSD17B10PPM1BPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023281040-A1 | STRAINED BI-FUNCTIONALIZED TRANS-CYCLOOCTENES | STICHTING RADBOUD UNIVERSITEIT (NL) | 2023-01-12 | — | — | WO | disclosed |