⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24879800 | 0.81 | — | — | |
| SCHEMBL21332639 | 0.74 | — | — | |
| SCHEMBL24631439 | 0.73 | — | — | |
| SCHEMBL24879895 | 0.63 | HTR3A (0.31) | — | |
| SCHEMBL31037927 | 0.58 | GRM2 (0.33) | — | |
| SCHEMBL19991554 | 0.57 | — | — | |
| SCHEMBL23240269 | 0.57 | — | — | |
| SCHEMBL24880383 | 0.56 | ALDH1A1 (0.47) | — | |
| SCHEMBL1848539 | 0.56 | — | — | |
| SCHEMBL24880230 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594680-A | TEAD inhibitor | 武汉人福创新药物研发中心有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| WO-2023280254-A1 | TEAD INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2023-01-12 | — | — | WO | disclosed |