Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 13/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31037911 | 0.82 | PIK3CB (0.37) | — | |
| SCHEMBL31037904 | 0.67 | POLB (0.44) | GRM2MAPTL3MBTL1HRH4 | |
| SCHEMBL7882986 | 0.67 | PTPN11 (0.36) | GRM2HRH4 | |
| SCHEMBL24879895 | 0.66 | HTR3A (0.31) | — | |
| SCHEMBL31546213 | 0.66 | POLB (0.50) | MAPT | |
| SCHEMBL31037926 | 0.65 | POLB (0.52) | MAPT | |
| SCHEMBL30998315 | 0.64 | EGFR (0.37) | — | |
| SCHEMBL31546231 | 0.62 | GRM2 (0.38) | GRM2HRH4 | |
| SCHEMBL28722181 | 0.60 | GAA (0.43) | BACE1 | |
| SCHEMBL29496124 | 0.60 | GAA (0.43) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119731163-A | KIF18A inhibitor compound, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-118666851-A | Condensed ring KIF18A inhibitor compound, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-09-20 | — | — | CN | disclosed |