Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.49 |
| ▸ | LIPE | Q05469 | 4/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22585908 | 0.84 | DHODH (0.44) | DHODH | |
| SCHEMBL25955371 | 0.82 | EGFR (0.35) | DHODH | |
| SCHEMBL25431556 | 0.82 | PIP4K2A (0.40) | EPHX2DHODH | |
| SCHEMBL20552809 | 0.79 | LIPE (0.52) | EPHX2LIPETRPV1 | |
| SCHEMBL30544066 | 0.79 | LIPE (0.52) | EPHX2LIPETRPV1 | |
| SCHEMBL25426624 | 0.77 | LIPE (0.55) | LIPE | |
| SCHEMBL25042801 | 0.76 | LIPE (0.46) | EPHX2LIPE | |
| SCHEMBL26674609 | 0.75 | LIPE (0.36) | LIPEDHODH | |
| SCHEMBL30641310 | 0.75 | LIPE (0.36) | LIPEDHODH | |
| SCHEMBL16967950 | 0.75 | LPL (0.35) | LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594680-A | TEAD inhibitor | 武汉人福创新药物研发中心有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| WO-2023280254-A1 | TEAD INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2023-01-12 | — | — | WO | disclosed |
| WO-2023280254-A1 | TEAD INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2023-01-12 | — | — | WO | disclosed |