Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 8/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.33 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30641310 | 1.00 | LIPE (0.36) | LIPECXCR2IRAK1MAT2APOLB | |
| SCHEMBL22574535 | 0.83 | LPL (0.37) | LIPECXCR2POLB | |
| SCHEMBL16967950 | 0.78 | LPL (0.35) | LIPECXCR2 | |
| SCHEMBL26674635 | 0.77 | LIPE (0.43) | LIPECXCR2 | |
| SCHEMBL24879916 | 0.75 | EPHX2 (0.49) | LIPEDHODH | |
| SCHEMBL31441746 | 0.74 | LRRK2 (0.33) | LIPE | |
| SCHEMBL29879749 | 0.74 | LIPE (0.42) | LIPE | |
| SCHEMBL25300352 | 0.74 | LIPE (0.42) | LIPE | |
| SCHEMBL9955932 | 0.74 | LIPE (0.38) | LIPECXCR2DGAT1 | |
| SCHEMBL27449514 | 0.73 | CASP6 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4526293-A1 | HETEROARENES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME | Repare Therapeutics Inc. (CA) | 2025-03-26 | — | — | EP | disclosed |
| WO-2023220831-A1 | HETEROARENES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME | REPARE THERAPEUTICS INC. (CA) | 2023-11-23 | — | — | WO | disclosed |