Zinc Ion

Zinc Ion

SCHEMBL2488066

O=S(=O)([O-])COc1ccccc1O.O=S(=O)([O-])COc1ccccc1O.[Zn+2]

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.52
JAK2 O60674 1/20 0.52
LMNA P02545 1/20 0.52
MAPT P10636 1/20 0.52
APP P05067 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
TSHR P16473 2/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
TP53 P04637 1/20 0.41
HPGD P15428 3/20 0.41
HSD11B1 P28845 1/20 0.41
HSD17B3 P37058 1/20 0.41
ATM Q13315 1/20 0.41
DRD2 P14416 1/20 0.39
DRD4 P21917 1/20 0.39
DRD3 P35462 1/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10884904 0.96 GAA (0.52) GAAJAK2LMNAMAPTAPP
Potassium Ion SCHEMBL21242 0.96 GAA (0.52) GAAJAK2LMNAMAPTAPP
Water SCHEMBL4072824 0.95 GAA (0.50) GAAJAK2LMNAMAPTAPP
SCHEMBL560229 0.81 GAA (0.55) GAAJAK2LMNAMAPTAPP
SCHEMBL6460144 0.77 GAA (0.56) GAAJAK2LMNAMAPTAPP
1-Hydroxy-2-Ethoxybenzene SCHEMBL28239263 0.72 GAA (0.53) GAAJAK2LMNAMAPTAPP
SCHEMBL5583798 0.71 GAA (0.44) GAAJAK2LMNAMAPTAPP
SCHEMBL28100659 0.71 HSD11B1 (0.51) GAAJAK2LMNAMAPTAPP
SCHEMBL1937408 0.71 HSD11B1 (0.51) GAAJAK2LMNAMAPTSMN1; SMN2
SCHEMBL2637278 0.71 GAA (0.95) GAAJAK2LMNAMAPTAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1587477-B1 ODORLESS FORMULATION FOR TREATING MUCOSAL DISCONTINUITIES EPIEN MEDICAL INC (US) 2011-10-26 EP claimed
EP-1587477-B1 ODORLESS FORMULATION FOR TREATING MUCOSAL DISCONTINUITIES EPIEN MEDICAL INC (US) 2011-10-26 EP disclosed