Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.45 |
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.45 |
| ▸ | CA12 known ✓ | O43570 | 2/20 | 0.44 |
| ▸ | ESR2 known ✓ | Q92731 | 2/20 | 0.42 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.36 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4094195 | 0.84 | ELANE (0.40) | HSD11B1HSD17B3CA1CA2CA12 | |
| SCHEMBL7156677 | 0.82 | ESR1 (0.62) | GAAKMT2AMEN1ESR1ESR2 | |
| SCHEMBL28100659 | 0.80 | HSD11B1 (0.51) | HSD11B1HSD17B3CA1CA2TP53 | |
| SCHEMBL7158425 | 0.80 | KMT2A (0.41) | HSD11B1HSD17B3TP53GAAKMT2A | |
| SCHEMBL7159703 | 0.79 | GAA (0.50) | TP53GAAKMT2AMEN1ESR1 | |
| SCHEMBL235067 | 0.78 | HSD11B1 (0.50) | HSD11B1HSD17B3CA1CA2TP53 | |
| SCHEMBL1075941 | 0.78 | CA1 (0.52) | HSD11B1HSD17B3CA1CA2TP53 | |
| SCHEMBL29382842 | 0.78 | HSD11B1 (0.50) | HSD11B1HSD17B3CA1CA2TP53 | |
| SCHEMBL2001002 | 0.77 | HSD11B1 (0.53) | HSD11B1HSD17B3CA1CA2TP53 | |
| SCHEMBL9541027 | 0.77 | HSD11B1 (0.49) | HSD11B1HSD17B3CA1CA2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11835532-B2 | Green concentrated reagent for hemotology systems | BECKMAN COULTER, INC. (US) | 2023-12-05 | — | — | US | disclosed |
| EP-3794346-B1 | GREEN CONCENTRATED REAGENT FOR HEMATOLOGY SYSTEMS | BECKMAN COULTER INC (US) | 2023-03-08 | — | — | EP | disclosed |
| US-20230047876-A1 | GREEN CONCENTRATED REAGENT FOR HEMOTOLOGY SYSTEMS | BECKMAN COULTER, INC. | 2023-02-16 | — | — | US | disclosed |
| US-11519921-B2 | Green concentrated reagent for hematology systems | BECKMAN COULTER, INC. (US) | 2022-12-06 | — | — | US | disclosed |
| US-20210231687-A1 | GREEN CONCENTRATED REAGENT FOR HEMATOLOGY SYSTEMS | BECKMAN COULTER, INC. | 2021-07-29 | — | — | US | disclosed |
| EP-3794346-A1 | GREEN CONCENTRATED REAGENT FOR HEMATOLOGY SYSTEMS | Beckman Coulter, Inc. (US) | 2021-03-24 | — | — | EP | disclosed |
| CN-112166322-A | Green concentrated reagent for hematology system | 拜克门寇尔特公司 | 2021-01-01 | — | — | CN | disclosed |
| US-20110268818-A1 | NGAL-BINDING SIDEROPHORES AND USE THEREOF TO TREAT IRON DEFICIENCY AND IRON OVERLOAD | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-11-03 | — | — | US | disclosed |
| EP-2330897-A1 | NGAL-BINDING SIDEROPHORES AND USE THEREOF TO TREAT IRON DEFICIENCY AND IRON OVERLOAD | The Trustees of Columbia University in the City of New York (US) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010033847-A1 | NGAL-BINDING SIDEROPHORES AND USE THEREOF TO TREAT IRON DEFICIENCY AND IRON OVERLOAD | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2010-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110268818-A1 | NGAL-BINDING SIDEROPHORES AND USE THEREOF TO TREAT IRON DEFICIENCY AND IRON OVERLOAD | SLC40A1, HAMP, TFRC | CA1 2702/4885CA2 1383/4885CA12 1332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.