Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | LGMN | Q99538 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14485084 | 0.84 | NPC1 (0.52) | ALDH1A1SMN1; SMN2LMNAHPGDLGMN | |
| SCHEMBL14804169 | 0.83 | LGMN (0.45) | ALDH1A1SMN1; SMN2LMNAHPGDLGMN | |
| SCHEMBL29931972 | 0.82 | ATM (0.48) | ALDH1A1SMN1; SMN2LMNAHPGDLGMN | |
| SCHEMBL855383 | 0.82 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNAHPGDLGMN | |
| SCHEMBL17543165 | 0.82 | ATM (0.48) | ALDH1A1SMN1; SMN2LMNAHPGDLGMN | |
| SCHEMBL31312959 | 0.82 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNAHPGDLGMN | |
| SCHEMBL27452092 | 0.82 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2HPGDLGMNGAA | |
| SCHEMBL17543650 | 0.81 | POLB (0.48) | ALDH1A1SMN1; SMN2LMNAHPGDLGMN | |
| SCHEMBL25964567 | 0.81 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2LMNAHPGDGAA | |
| SCHEMBL12684501 | 0.80 | MAPK8 (0.41) | ALDH1A1SMN1; SMN2LMNAHPGDLGMN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280237-A1 | SYNTHESIS AND APPLICATION OF PHOSPHATASE DEGRADER | 海创药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |