Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24880897 | 0.85 | OPRD1 (0.31) | OPRD1 | |
| SCHEMBL24881058 | 0.84 | OPRD1 (0.32) | OPRD1 | |
| SCHEMBL24881076 | 0.84 | OPRD1 (0.32) | OPRD1 | |
| SCHEMBL24881630 | 0.84 | OPRD1 (0.32) | OPRD1 | |
| SCHEMBL24881632 | 0.83 | ATAD2 (0.31) | — | |
| SCHEMBL24881625 | 0.83 | ATAD2 (0.31) | — | |
| SCHEMBL24881620 | 0.83 | ATAD2 (0.31) | — | |
| SCHEMBL24880898 | 0.83 | SIGMAR1 (0.33) | — | |
| SCHEMBL24880956 | 0.80 | KDM4E (0.33) | OPRD1 | |
| SCHEMBL24880949 | 0.80 | KDM4E (0.33) | OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280180-A1 | FUSED RING COMPOUND AS WEE-1 INHIBITOR | 微境生物医药科技(上海)有限公司 | 2023-01-12 | — | — | WO | disclosed |