Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 4/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 4/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 2/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15731444 | 0.83 | KDM4E (0.39) | PIM1PIM3PIM2HTR2AHTR2C | |
| SCHEMBL4418262 | 0.74 | GRM2 (0.46) | PIM1PIM3MEN1ALDH1A1HPGD | |
| SCHEMBL1157421 | 0.72 | ALPL (0.39) | MEN1ALDH1A1KMT2AALPL | |
| SCHEMBL1157418 | 0.72 | ATM (0.41) | MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL30963624 | 0.71 | SLC6A4 (0.37) | MPOSLC6A2SLC6A3ALPLHTR2A | |
| SCHEMBL23646859 | 0.71 | SLC6A4 (0.37) | MPOSLC6A2SLC6A3ALPLHTR2A | |
| SCHEMBL29011777 | 0.70 | ALDH1A1 (0.37) | PIM1PIM3PIM2MEN1ALDH1A1 | |
| SCHEMBL1156832 | 0.70 | MAPK14 (0.34) | MEN1ALDH1A1THRBHPGDKMT2A | |
| SCHEMBL30927887 | 0.70 | GPBAR1 (0.42) | PIM1PIM3PIM2MPOSLC6A4 | |
| SCHEMBL26277883 | 0.69 | MPO (0.38) | MPOSLC6A2SLC6A3HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280293-A1 | PYRROLE SULFONYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 天地恒一制药股份有限公司 | 2023-01-12 | — | — | WO | disclosed |