Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30078150 | 1.00 | LMNA (0.48) | LMNAMAPTTNKS2RAF1BRPF1 | |
| SCHEMBL30692234 | 0.83 | LMNA (0.56) | LMNAMAPTBRPF1TP53PGR | |
| SCHEMBL1639030 | 0.83 | LMNA (0.56) | LMNAMAPTBRPF1TP53PGR | |
| SCHEMBL12322303 | 0.77 | GRIA1 (0.58) | MAPTTNKS2RAF1GRIK1GRIA1 | |
| SCHEMBL2522765 | 0.75 | LMNA (0.58) | LMNAMAPTBRPF1PGRDAO | |
| SCHEMBL29859942 | 0.75 | LMNA (0.58) | LMNAMAPTBRPF1PGRDAO | |
| Hydrochloric Acid SCHEMBL19384637 | 0.74 | LMNA (0.56) | LMNAMAPTBRPF1PGRDAO | |
| SCHEMBL3263393 | 0.72 | DAO (0.66) | LMNAMAPTTP53PGRDAO | |
| SCHEMBL25681022 | 0.69 | ATAD2 (0.55) | LMNAMAPTPGRGRIA1GRIA2 | |
| SCHEMBL3783964 | 0.69 | ALDH1A1 (0.54) | LMNAMAPTRAF1TP53MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283369-A1 | MODULATORS OF PROTEIN KINASES | VIBLIOME THERAPEUTICS, LLC (US) | 2023-01-12 | — | — | WO | disclosed |