Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.39 |
| ▸ | TDO2 | P48775 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24890808 | 1.00 | ATR (0.48) | ATRL3MBTL1HRH4TDO2MAPK1 | |
| SCHEMBL3101453 | 0.82 | L3MBTL1 (0.42) | ATRL3MBTL1HRH4TDO2MAPK1 | |
| SCHEMBL9350414 | 0.82 | L3MBTL1 (0.42) | ATRL3MBTL1HRH4TDO2MAPK1 | |
| SCHEMBL13353984 | 0.81 | TDO2 (0.37) | ATRL3MBTL1HRH4TDO2HRH2 | |
| SCHEMBL24890645 | 0.81 | TDO2 (0.37) | ATRL3MBTL1HRH4TDO2HRH2 | |
| SCHEMBL17187742 | 0.80 | ATR (0.47) | ATRL3MBTL1HRH4TDO2MAPK1 | |
| SCHEMBL24248254 | 0.77 | ATR (0.36) | ATRFEN1ALOX5AP | |
| SCHEMBL24890646 | 0.76 | TDO2 (0.33) | ATRTDO2HRH2HRH3FEN1 | |
| SCHEMBL15205265 | 0.74 | MAPKAPK2 (0.41) | ATRHRH4MAPK1MAPKAPK2 | |
| SCHEMBL28563124 | 0.72 | TDO2 (0.37) | TDO2HRH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284249-A1 | IMIDAZOPYRAZINONE FLUORESCEIN AND PREPARATION METHOD THEREFOR | 中国科学院深圳先进技术研究院 | 2023-01-19 | — | — | WO | disclosed |