SCHEMBL24891350

SCHEMBL24891350

O=c1oc(=O)c2ccccc3c(=O)oc(=O)c3ccccc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 6/20 0.61
ALDH1A1 P00352 4/20 0.61
SMN1; SMN2 Q16637 3/20 0.61
MAPT P10636 3/20 0.61
NPSR1 Q6W5P4 3/20 0.61
LMNA P02545 3/20 0.61
HSD17B10 Q99714 2/20 0.61
GMNN O75496 1/20 0.61
TP53 P04637 1/20 0.61
CYP1A2 P05177 1/20 0.61
POLB P06746 1/20 0.61
CTSG P08311 1/20 0.61
CTSA P10619 1/20 0.61
CYP2D6 P10635 1/20 0.61
CYP2C9 P11712 1/20 0.61
ALOX15 P16050 1/20 0.61
NFKB1 P19838 1/20 0.61
CYP2C19 P33261 1/20 0.61
THPO P40225 1/20 0.61
MTOR P42345 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29391754 0.97 ALDH1A1 (0.58) ELANEALDH1A1SMN1; SMN2MAPTNPSR1
SCHEMBL257 0.97 ALDH1A1 (0.58) ELANEALDH1A1SMN1; SMN2MAPTNPSR1
SCHEMBL30966887 0.97 ALDH1A1 (0.58) ELANEALDH1A1SMN1; SMN2MAPTNPSR1
SCHEMBL28252904 0.94 NPSR1 (0.57) ELANEALDH1A1SMN1; SMN2MAPTNPSR1
SCHEMBL29599746 0.94 NPSR1 (0.57) ELANEALDH1A1SMN1; SMN2MAPTNPSR1
SCHEMBL20963057 0.93 ELANE (0.54) ELANEALDH1A1SMN1; SMN2MAPTNPSR1
SCHEMBL21173973 0.90 ELANE (0.52) ELANEALDH1A1SMN1; SMN2MAPTNPSR1
SCHEMBL31481273 0.89 ELANE (0.52) ELANEALDH1A1SMN1; SMN2MAPTNPSR1
SCHEMBL21961896 0.88 ELANE (0.56) ELANEALDH1A1SMN1; SMN2MAPTNPSR1
SCHEMBL20963080 0.86 ALDH1A1 (0.46) ELANEALDH1A1SMN1; SMN2MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3453733-B1 POLYIMIDE RESIN, POLYIMIDE RESIN COMPOSITION, AND POLYIMIDE FILM MITSUBISHI GAS CHEMICAL CO (JP) 2023-01-18 EP disclosed