SCHEMBL29599746

SCHEMBL29599746

O=c1oc(=O)c2ccc1c1ccccc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 4/20 0.57
RXFP1 Q9HBX9 3/20 0.57
ALDH1A1 P00352 4/20 0.56
MAPT P10636 4/20 0.56
LMNA P02545 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
ELANE P08246 3/20 0.56
HSD17B10 Q99714 2/20 0.56
GMNN O75496 1/20 0.56
TP53 P04637 1/20 0.56
CYP1A2 P05177 1/20 0.56
POLB P06746 1/20 0.56
CTSG P08311 1/20 0.56
CTSA P10619 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
ALOX15 P16050 1/20 0.56
NFKB1 P19838 1/20 0.56
CYP2C19 P33261 1/20 0.56
THPO P40225 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28252904 1.00 NPSR1 (0.57) NPSR1RXFP1ALDH1A1MAPTLMNA
SCHEMBL29391754 0.97 ALDH1A1 (0.58) NPSR1RXFP1ALDH1A1MAPTLMNA
SCHEMBL257 0.97 ALDH1A1 (0.58) NPSR1RXFP1ALDH1A1MAPTLMNA
SCHEMBL30966887 0.97 ALDH1A1 (0.58) NPSR1RXFP1ALDH1A1MAPTLMNA
SCHEMBL24891350 0.94 ELANE (0.61) NPSR1RXFP1ALDH1A1MAPTLMNA
SCHEMBL21173973 0.91 ELANE (0.52) NPSR1RXFP1ALDH1A1MAPTLMNA
SCHEMBL20963057 0.88 ELANE (0.54) NPSR1RXFP1ALDH1A1MAPTLMNA
SCHEMBL20963080 0.87 ALDH1A1 (0.46) NPSR1RXFP1ALDH1A1MAPTLMNA
SCHEMBL31634612 0.83 ALDH2 (0.48) NPSR1RXFP1ALDH1A1MAPTLMNA
SCHEMBL31481273 0.83 ELANE (0.52) NPSR1RXFP1ALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3512905-B1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2022-08-24 EP disclosed
CN-109790292-B Process for preparing polybenzazole polymer (P) 巴斯夫欧洲公司 2022-05-31 CN disclosed