SCHEMBL21961896

SCHEMBL21961896

O=c1oc(=O)c2ccccc2c(=O)o1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 6/20 0.56
ALDH1A1 P00352 4/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
NPSR1 Q6W5P4 3/20 0.56
MAPT P10636 3/20 0.56
LMNA P02545 3/20 0.56
HSD17B10 Q99714 2/20 0.56
GMNN O75496 1/20 0.56
TP53 P04637 1/20 0.56
CYP1A2 P05177 1/20 0.56
POLB P06746 1/20 0.56
CTSG P08311 1/20 0.56
CTSA P10619 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
ALOX15 P16050 1/20 0.56
NFKB1 P19838 1/20 0.56
CYP2C19 P33261 1/20 0.56
THPO P40225 1/20 0.56
MTOR P42345 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24891350 0.88 ELANE (0.61) ELANEALDH1A1SMN1; SMN2NPSR1MAPT
SCHEMBL29391754 0.85 ALDH1A1 (0.58) ELANEALDH1A1SMN1; SMN2NPSR1MAPT
SCHEMBL30966887 0.85 ALDH1A1 (0.58) ELANEALDH1A1SMN1; SMN2NPSR1MAPT
SCHEMBL257 0.85 ALDH1A1 (0.58) ELANEALDH1A1SMN1; SMN2NPSR1MAPT
SCHEMBL8958450 0.85 KDM4E (0.62) ALDH1A1SMN1; SMN2MAPTLMNAHSD17B10
SCHEMBL28252904 0.82 NPSR1 (0.57) ELANEALDH1A1SMN1; SMN2NPSR1MAPT
SCHEMBL29599746 0.82 NPSR1 (0.57) ELANEALDH1A1SMN1; SMN2NPSR1MAPT
SCHEMBL20963057 0.81 ELANE (0.54) ELANEALDH1A1SMN1; SMN2NPSR1MAPT
SCHEMBL30880452 0.80 ESR2 (0.57) ELANEALDH1A1SMN1; SMN2NPSR1MAPT
SCHEMBL21173973 0.79 ELANE (0.52) ELANEALDH1A1SMN1; SMN2NPSR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12612482-B2 Combination of crosslinkers to improve coating properties BASF SE (DE) 2026-04-28 US disclosed
CN-113330086-B curable composition 巴斯夫欧洲公司 2023-11-03 CN disclosed
US-20230012924-A1 COMBINATION OF CROSSLINKERS TO IMPROVE COATING PROPERTIES BASF SE (DE) 2023-01-19 US disclosed
US-20220380591-A1 CURABLE COMPOSITIONS WITH ACRYLIC AND SILICONE RESINS BASF SE (DE) 2022-12-01 US disclosed
EP-4077405-A1 COMBINATION OF CROSSLINKERS TO IMPROVE COATING PROPERTIES BASF SE (DE) 2022-10-26 EP disclosed
EP-4034601-A1 CURABLE COMPOSITIONS WITH ACRYLIC AND SILICONE RESINS BASF SE (DE) 2022-08-03 EP disclosed
US-20210403772-A1 CURABLE ADHESIVE COMPOSITION BASF SE (DE) 2021-12-30 US disclosed
EP-3880764-A2 CURABLE COMPOSITION BASF SE (DE) 2021-09-22 EP disclosed
WO-2021126780-A1 COMBINATION OF CROSSLINKERS TO IMPROVE COATING PROPERTIES BASF SE (DE) 2021-06-24 WO disclosed
WO-2021061533-A1 CURABLE COMPOSITIONS WITH ACRYLIC AND SILICONE RESINS BASF SE (DE) 2021-04-01 WO disclosed
WO-2020102801-A2 CURABLE COMPOSITION BASF SE (DE) 2020-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612482-B2 Combination of crosslinkers to improve coating properties BHMT2, FDFT1, MNAT1 ELANE 3647/4885ALDH1A1 619/4885SMN1; SMN2 588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.