Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9927903 | 1.00 | HRH3 (0.48) | HRH3SIGMAR1CARM1PRMT6PRMT8 | |
| SCHEMBL12555 | 1.00 | HRH3 (0.48) | HRH3SIGMAR1CARM1PRMT6PRMT8 | |
| SCHEMBL24891389 | 1.00 | HRH3 (0.48) | HRH3SIGMAR1CARM1PRMT6PRMT8 | |
| SCHEMBL24891390 | 1.00 | HRH3 (0.48) | HRH3SIGMAR1CARM1PRMT6PRMT8 | |
| SCHEMBL3671614 | 0.97 | SIGMAR1 (0.46) | HRH3SIGMAR1CARM1PRMT6PRMT8 | |
| SCHEMBL9927905 | 0.92 | — | — | |
| SCHEMBL2231151 | 0.86 | PIM1 (0.42) | SIGMAR1 | |
| SCHEMBL1186740 | 0.86 | — | — | |
| SCHEMBL7649376 | 0.85 | HRH3 (0.56) | HRH3SIGMAR1SLC6A4 | |
| SCHEMBL791946 | 0.84 | SIGMAR1 (0.58) | SIGMAR1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119553-A1 | COMPOUND USED AS KINASE INHIBITOR AND USE THEREOF | TYK Medicines (Zhengzhou), Inc. (CN) | 2023-01-18 | — | — | EP | disclosed |