SCHEMBL12555

SCHEMBL12555

CN(C)CCN1CCCCC1

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 3/20 0.48
SIGMAR1 Q99720 9/20 0.44
CARM1 Q86X55 1/20 0.42
PRMT6 Q96LA8 1/20 0.42
PRMT8 Q9NR22 1/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9927903 1.00 HRH3 (0.48) HRH3SIGMAR1CARM1PRMT6PRMT8
SCHEMBL24891389 1.00 HRH3 (0.48) HRH3SIGMAR1CARM1PRMT6PRMT8
SCHEMBL24891390 1.00 HRH3 (0.48) HRH3SIGMAR1CARM1PRMT6PRMT8
SCHEMBL24891404 1.00 HRH3 (0.48) HRH3SIGMAR1CARM1PRMT6PRMT8
SCHEMBL3671614 0.97 SIGMAR1 (0.46) HRH3SIGMAR1CARM1PRMT6PRMT8
SCHEMBL9927905 0.92
SCHEMBL2231151 0.86 PIM1 (0.42) SIGMAR1
SCHEMBL1186740 0.86
SCHEMBL7649376 0.85 HRH3 (0.56) HRH3SIGMAR1SLC6A4
SCHEMBL791946 0.84 SIGMAR1 (0.58) SIGMAR1SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 819 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11753408-B2 Compounds and method for blocking transmission of malarial parasite THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-09-12 US claimed
US-9279054-B2 Sound-absorbent foam system PREFORM GMBH (DE) 2016-03-08 US claimed
US-20140171431-A1 AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES (CN) 2014-06-19 US claimed
EP-2725024-A1 AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) 2014-04-30 EP claimed
US-20110057144-A1 SOUND-ABSORBENT FOAM SYSTEM PREFORM GMBH (DE) 2011-03-10 US claimed
EP-2090621-B1 Sound absorbing foam system PREFORM GMBH (DE) 2009-12-23 EP claimed
WO-2009103420-A1 SOUND-ABSORBENT FOAM SYSTEM PREFORM GMBH (DE) 2009-08-27 WO claimed
EP-2090621-A1 Sound absorbing foam system Preform GmbH (DE) 2009-08-19 EP claimed
EP-0604363-B1 Stable solutions of accelerators for epoxy resins VANTICO AG (CH) 2003-02-12 EP claimed
US-6479672-B1 Diastereoselective preparation of Michael adducts MERCK & CO., INC. 2002-11-12 US claimed
US-5470896-A Storage-stable solutions of accelerator systems CIBA-GEIGY CORPORATION (US) 1995-11-28 US claimed
EP-0604363-A2 Stable solutions of accelerators for epoxy resins CIBA-GEIGY AG (CH) 1994-06-29 EP claimed
US-12612485-B2 Continuous production of polyurethane prepolymers BASF SE (DE) 2026-04-28 US disclosed
EP-4720146-A1 RIGID POLYISOCYANURATE FOAMS OBTAINABLE USING POLYETHYLENE TEREPHTHALATE-BASED ESTERS BASF SE (DE) 2026-04-08 EP disclosed
US-12559586-B2 Compositions containing uretdione groups crosslinking at low temperatures COVESTRO DEUTSCHLAND AG (DE) 2026-02-24 US disclosed
EP-4601880-B1 RETORTABLE SOLVENT FREE LAMINATION ADHESIVES SUN CHEMICAL BV (NL) 2026-02-18 EP disclosed
EP-0433889-A2 Process for the preparation of polyurethane soft foams with low compression hardness and mixtures of polyoxypropylene-polyoxyethylene block polyols suitable therefor BASF Aktiengesellschaft (DE) 1991-06-26 EP disclosed
EP-0433878-A2 Process for the preparation of flexible polyurethane foams with viscoelastic, body-sound damping properties and the polyalkoxide-polyol blends for this process BASF Aktiengesellschaft (DE) 1991-06-26 EP disclosed
EP-0377891-A2 Process for the preparation of fire-retardant elastic flexible polyurethane foams, and low viscosity melamine polyether dispersions therefor BASF Aktiengesellschaft (DE) 1990-07-18 EP disclosed
EP-0219706-A1 N,N-dialkylaminoalkyl-hexahydro-5-oxo-1H-pyrrolizine-3-carboxamides WARNER-LAMBERT COMPANY (US) 1987-04-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559586-B2 Compositions containing uretdione groups crosslinking at low temperatures URB2, UQCRB, UQCRC2 HRH3 93/4885SIGMAR1 400/4885CARM1 779/4885
US-12612485-B2 Continuous production of polyurethane prepolymers UROD, HPD, PGD HRH3 2479/4885SIGMAR1 2486/4885CARM1 3314/4885
US-20140171431-A1 AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE PLA2G5, LTA4H, PLA2G4A HRH3 559/4885SIGMAR1 4568/4885CARM1 3258/4885
US-11753408-B2 Compounds and method for blocking transmission of malarial parasite PLK1, HSP90B1, CEP170 HRH3 2849/4885SIGMAR1 1506/4885CARM1 3076/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.