Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.51 |
| ▸ | P4HTM | Q9NXG6 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891848 | 0.86 | P4HTM (0.46) | ALDH1A1NPC1RAB9AKDM4EPRKAA2 | |
| SCHEMBL24892187 | 0.84 | RAB9A (0.71) | ALDH1A1NPC1RAB9AKDM4EPRKAA2 | |
| SCHEMBL30182474 | 0.84 | RAB9A (0.71) | ALDH1A1NPC1RAB9AKDM4EPRKAA2 | |
| SCHEMBL24891680 | 0.81 | NPC1 (0.42) | ALDH1A1NPC1RAB9AKDM4EP4HTM | |
| SCHEMBL30182527 | 0.78 | NAMPT (0.59) | ALDH1A1NPC1RAB9AKDM4EPRKAA2 | |
| SCHEMBL30182102 | 0.78 | NAMPT (0.59) | ALDH1A1NPC1RAB9AKDM4EPRKAA2 | |
| SCHEMBL24891789 | 0.78 | NAMPT (0.59) | ALDH1A1NPC1RAB9AKDM4EPRKAA2 | |
| SCHEMBL24891973 | 0.78 | NAMPT (0.59) | ALDH1A1NPC1RAB9AKDM4EPRKAA2 | |
| SCHEMBL24892240 | 0.78 | P4HTM (0.75) | ALDH1A1NPC1RAB9AKDM4EP4HTM | |
| SCHEMBL21646078 | 0.77 | ALDH1A1 (0.64) | ALDH1A1NPC1RAB9AKDM4EP4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |