Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.49 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.49 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24892014 | 0.94 | KDM1A (0.53) | HDAC3HDAC11HDAC8HDAC6DEGS1 | |
| Trifluoroacetic Acid SCHEMBL30182557 | 0.91 | HDAC3 (0.47) | HDAC3HDAC11HDAC8HDAC6DEGS1 | |
| SCHEMBL24892136 | 0.81 | ACR (0.39) | — | |
| Trifluoroacetic Acid SCHEMBL30182236 | 0.75 | KDM4E (0.39) | KDM1AMAOA | |
| SCHEMBL24891879 | 0.74 | MAPT (0.64) | HDAC8HDAC6 | |
| SCHEMBL24669978 | 0.74 | MAPT (0.64) | HDAC8HDAC6 | |
| SCHEMBL24891830 | 0.72 | KMT2A (0.64) | — | |
| SCHEMBL24891968 | 0.72 | HDAC3 (0.64) | HDAC3HDAC11HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL8994029 | 0.71 | F2 (0.71) | — | |
| SCHEMBL20284041 | 0.71 | DEGS1 (1.00) | HDAC3HDAC11HDAC8HDAC6DEGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |