Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.39 |
| ▸ | ACR | P10323 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24892136 | 0.93 | ACR (0.39) | ACR | |
| Trifluoroacetic Acid SCHEMBL30182557 | 0.83 | HDAC3 (0.47) | KDM4EKDM6BKDM1AMAOAMAOB | |
| Trifluoroacetic Acid SCHEMBL30182338 | 0.83 | SLC2A1 (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL30182694 | 0.83 | — | — | |
| SCHEMBL24892002 | 0.75 | HDAC3 (0.55) | KDM1AMAOA | |
| Trifluoroacetic Acid SCHEMBL30182432 | 0.74 | MAPT (0.42) | KDM4EACRKLK1KLK5 | |
| SCHEMBL24891979 | 0.74 | CHIA (0.47) | — | |
| SCHEMBL24892064 | 0.74 | — | — | |
| Trifluoroacetic Acid SCHEMBL30182754 | 0.74 | MAPKAPK2 (0.51) | ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL30182598 | 0.73 | ACR (0.41) | ACR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |