Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.53 |
| ▸ | MAOA | P21397 | 6/20 | 0.53 |
| ▸ | KDM1B | Q8NB78 | 6/20 | 0.53 |
| ▸ | RCOR1 | Q9UKL0 | 6/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24892002 | 0.94 | HDAC3 (0.55) | KDM1AMAOAKDM1BRCOR1HDAC3 | |
| Trifluoroacetic Acid SCHEMBL30182557 | 0.85 | HDAC3 (0.47) | KDM1AMAOAKDM1BRCOR1HDAC3 | |
| SCHEMBL24892136 | 0.75 | ACR (0.39) | — | |
| SCHEMBL29536946 | 0.72 | KDM1A (0.62) | KDM1AMAOAKDM1BRCOR1HDAC3 | |
| SCHEMBL1993714 | 0.72 | KDM1A (0.62) | KDM1AMAOAKDM1BRCOR1HDAC3 | |
| SCHEMBL29802853 | 0.70 | NAMPT (0.43) | TMPRSS2 | |
| SCHEMBL12333904 | 0.70 | KDM1A (0.73) | KDM1AMAOAKDM1BRCOR1HDAC3 | |
| Trifluoroacetic Acid SCHEMBL30182236 | 0.70 | KDM4E (0.39) | KDM1AMAOAMAOB | |
| SCHEMBL24891879 | 0.69 | MAPT (0.64) | HDAC8HDAC6 | |
| SCHEMBL24669978 | 0.69 | MAPT (0.64) | HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |