Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16520280 | 0.91 | KMT2A (0.52) | KMT2AMEN1LMNACYP3A4NPC1 | |
| SCHEMBL2853759 | 0.89 | CES2 (0.55) | KMT2AMEN1LMNACYP3A4NPC1 | |
| SCHEMBL13719843 | 0.89 | LMNA (0.63) | KMT2AMEN1LMNACYP3A4NPC1 | |
| SCHEMBL8165449 | 0.87 | CYP3A4 (0.66) | KMT2AMEN1LMNACYP3A4CA1 | |
| SCHEMBL3884023 | 0.87 | BCHE (0.50) | KMT2AMEN1LMNANPSR1BCHE | |
| SCHEMBL10795242 | 0.86 | KMT2A (0.47) | KMT2AMEN1LMNACYP3A4NPC1 | |
| SCHEMBL27829223 | 0.86 | KMT2A (0.47) | KMT2AMEN1LMNACYP3A4NPC1 | |
| SCHEMBL5580391 | 0.85 | ESR1 (0.51) | KMT2AMEN1LMNACYP3A4NPC1 | |
| SCHEMBL13461312 | 0.85 | CYP3A4 (0.50) | KMT2AMEN1LMNACYP3A4CA1 | |
| SCHEMBL5776640 | 0.85 | KMT2A (0.56) | KMT2AMEN1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102282154-B | Dimeric avermectin and milbemycin derivatives | MERIAL LTD | 2015-07-01 | — | — | CN | disclosed |
| EP-2376513-B1 | DIMERIC AVERMECTIN AND MILBEMYCIN DERIVATIVES | MERIAL LTD (US) | 2015-02-25 | — | — | EP | disclosed |
| EP-2376513-B1 | DIMERIC AVERMECTIN AND MILBEMYCIN DERIVATIVES | MERIAL LTD (US) | 2015-02-25 | — | — | EP | disclosed |
| EP-1154734-B1 | INJECTABLE COLLAGEN-BASED SYSTEM FOR DELIVERY OF CELLS | PROCHON BIOTECH LTD (IL) | 2014-10-01 | — | — | EP | disclosed |
| US-8426460-B2 | Dimeric avermectin and milbemycin derivatives | MERIAL LIMITED (US) | 2013-04-23 | — | — | US | disclosed |
| US-8426460-B2 | Dimeric avermectin and milbemycin derivatives | MERIAL LIMITED (US) | 2013-04-23 | — | — | US | disclosed |
| US-8426460-B2 | Dimeric avermectin and milbemycin derivatives | MERIAL LIMITED (US) | 2013-04-23 | — | — | US | disclosed |
| CN-102282154-A | Dimeric avermectin and milbemycin derivatives | — | 2011-12-14 | — | — | CN | disclosed |
| EP-2376513-A1 | DIMERIC AVERMECTIN AND MILBEMYCIN DERIVATIVES | Merial Limited (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010065852-A1 | DIMERIC AVERMECTIN AND MILBEMYCIN DERIVATIVES | MERIAL LIMITED (US) | 2010-06-10 | — | — | WO | disclosed |
| EP-0319990-B1 | Process for preparing composite membranes | DU PONT (US) | 1993-10-20 | — | — | EP | disclosed |
| EP-0213925-B1 | COPOLYMERIZABLE UV STABILIZERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-03-11 | — | — | EP | disclosed |
| EP-0319990-A2 | Process for preparing composite membranes | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-06-14 | — | — | EP | disclosed |
| US-4831109-A | Copolymerizable UV stabilizers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-05-16 | — | — | US | disclosed |
| US-4783346-A | INTERFACES, POLYAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-11-08 | — | — | US | disclosed |
| US-4691059-A | Copolymerizable UV stabilizers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-09-01 | — | — | US | disclosed |
| EP-0213925-A2 | Copolymerizable UV stabilizers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-03-11 | — | — | EP | disclosed |
| US-4366102-A | Process for the preparation of chloroformic acid aryl esters | BAYER AKTIENGESELLSCHAFT (DE) | 1982-12-28 | — | — | US | disclosed |
| US-4258164-A | Reticulate polymers based on oligourethanacrylates and method for their manufacture | BERLIN ALFRED A | 1981-03-24 | — | — | US | disclosed |
| US-4250322-A | Oligourethanacrylates and methods for their manufacture | ALTSHULER JUDIF M (SU) | 1981-02-10 | — | — | US | disclosed |