Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ACR | P10323 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30180974 | 0.93 | MAPT (0.47) | MAPTTP53KDM4EALDH1A1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL30182432 | 0.86 | MAPT (0.42) | MAPTTP53KDM4EALDH1A1CA12 | |
| SCHEMBL24892102 | 0.86 | MAPT (0.42) | MAPTTP53KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24892364 | 0.83 | ST14 (0.47) | MAPTKDM4ESMN1; SMN2CA12CA2 | |
| SCHEMBL24892357 | 0.77 | SMYD3 (0.42) | MAPTTP53ACRKMT2ANPC1 | |
| SCHEMBL24892100 | 0.75 | S1PR1 (0.47) | KDM4EALDH1A1SMN1; SMN2CNR1NPC1 | |
| SCHEMBL24892365 | 0.74 | ST14 (0.55) | MAPTKDM4ESMN1; SMN2CA12CA2 | |
| SCHEMBL24892123 | 0.73 | ALDH1A1 (0.45) | MAPTKDM4EALDH1A1SMN1; SMN2CNR1 | |
| SCHEMBL30180742 | 0.73 | ALDH1A1 (0.45) | MAPTKDM4EALDH1A1SMN1; SMN2CNR1 | |
| Trifluoroacetic Acid SCHEMBL30182598 | 0.70 | ACR (0.41) | ACRKMT2ANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |