Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PLAU | P00749 | 4/20 | 0.44 |
| ▸ | PLG | P00747 | 3/20 | 0.44 |
| ▸ | PLAT | P00750 | 3/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | KDM5C | P41229 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30180742 | 1.00 | ALDH1A1 (0.45) | ALDH1A1PLAUPLGPLATKLKB1 | |
| Trifluoroacetic Acid SCHEMBL30182466 | 0.93 | KDM4E (0.44) | ALDH1A1PLAUPLGPLATKLKB1 | |
| SCHEMBL24892100 | 0.85 | S1PR1 (0.47) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24891987 | 0.83 | ALDH1A1 (0.50) | ALDH1A1PLAUPLGPLATKLKB1 | |
| SCHEMBL24892365 | 0.82 | ST14 (0.55) | PLAUPLGPLATKLKB1PRSS1 | |
| SCHEMBL24670339 | 0.78 | TRPV1 (0.50) | PLAUPLGPLATKLKB1PRSS1 | |
| SCHEMBL24892364 | 0.77 | ST14 (0.47) | PLAUPLGPLATKLKB1PRSS1 | |
| SCHEMBL30180974 | 0.77 | MAPT (0.47) | ALDH1A1KDM4ESMN1; SMN2ST14CNR1 | |
| Trifluoroacetic Acid SCHEMBL30182473 | 0.76 | KDM4E (0.48) | ALDH1A1KDM4EKDM5CNPC1RAB9A | |
| SCHEMBL5213915 | 0.75 | NPC1 (0.67) | KDM4EKDM5BKDM5AKDM5CNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |