Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | KDM6B | O15054 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | KDM5C | P41229 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.48 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891987 | 0.92 | ALDH1A1 (0.50) | KDM4EALDH1A1LMNANPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL30182466 | 0.85 | KDM4E (0.44) | KDM4EKDM6BKDM1AMAOAMAOB | |
| SCHEMBL24891990 | 0.78 | ALDH1A1 (0.52) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL29803202 | 0.78 | NR1H4 (0.53) | KDM4ELMNANPC1RAB9AKMT2A | |
| Trifluoroacetic Acid SCHEMBL30182598 | 0.77 | ACR (0.41) | NPC1RAB9ASLC2A1KMT2ANR1H4 | |
| SCHEMBL24891909 | 0.76 | S1PR1 (0.55) | ALDH1A1NPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL24892123 | 0.76 | ALDH1A1 (0.45) | KDM4EKDM5CALDH1A1LMNANPC1 | |
| SCHEMBL30180742 | 0.76 | ALDH1A1 (0.45) | KDM4EKDM5CALDH1A1LMNANPC1 | |
| SCHEMBL23963298 | 0.75 | SMN1; SMN2 (0.58) | KDM4ENPC1RAB9ASMN1; SMN2KDR | |
| SCHEMBL23291297 | 0.75 | GAA (0.69) | KDM4EALDH1A1LMNAKMT2ALOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |