Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 3/20 | 0.46 |
| ▸ | PLAU | P00749 | 3/20 | 0.46 |
| ▸ | PLAT | P00750 | 3/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24892365 | 0.94 | ST14 (0.55) | TRPV1ST14MEN1KMT2AKDM4E | |
| Trifluoroacetic Acid SCHEMBL29803776 | 0.92 | MLYCD (0.49) | TRPV1ST14MEN1KMT2AKDM4E | |
| SCHEMBL24892364 | 0.86 | ST14 (0.47) | TRPV1ST14MEN1KMT2AKDM4E | |
| SCHEMBL24892106 | 0.81 | ALDH1A1 (0.46) | ST14MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL24892110 | 0.80 | KMT2A (0.56) | MEN1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL10695177 | 0.80 | TRPV1 (0.59) | TRPV1KDM4ENPC1RAB9AGALR3 | |
| SCHEMBL30180742 | 0.78 | ALDH1A1 (0.45) | ST14MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL24892123 | 0.78 | ALDH1A1 (0.45) | ST14MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL30503474 | 0.78 | ST14 (0.63) | ST14KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10694927 | 0.77 | TRPV1 (0.52) | TRPV1MEN1KMT2AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |