Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | KDM5C | P41229 | 3/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL766363 | 0.92 | PHF8 (0.52) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL19776948 | 0.89 | KMT2A (0.45) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL14785792 | 0.83 | EPHX2 (0.45) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL14785649 | 0.83 | EPHX2 (0.49) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL38654455 | 0.82 | ALDH1A1 (0.42) | KDM4EKMT2ALMNACYP1A2TSHR | |
| SCHEMBL490860 | 0.82 | KDM4E (0.46) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL9999327 | 0.82 | KDM4E (0.46) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL14785685 | 0.82 | PRMT1 (0.52) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL14785825 | 0.82 | PRMT1 (0.52) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL14785620 | 0.82 | PRMT1 (0.52) | PHF8KDM2AKDM4EKDM5CEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023288226-A2 | POLYMER ENGINEERED FORMS OF INTERFERON-GAMMA AND METHODS OF USE | NEKTAR THERAPEUTICS (US) | 2023-01-19 | — | — | WO | disclosed |