SCHEMBL24894035

SCHEMBL24894035

c1ccc2c(c1)Nc1cccc3c1N2c1ccccc1S3

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 6/20 0.48
GAA P10253 5/20 0.48
MAPT P10636 4/20 0.48
BCHE P06276 4/20 0.48
ACHE P22303 3/20 0.48
MAOA P21397 2/20 0.48
MEN1 O00255 2/20 0.48
CYP1A2 P05177 2/20 0.48
SLC6A2 P23975 2/20 0.48
HTR2C P28335 2/20 0.48
KMT2A Q03164 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
POLB P06746 1/20 0.48
CYP3A4 P08684 1/20 0.48
ADORA3 P0DMS8 1/20 0.48
ALOX15 P16050 1/20 0.48
ALOX12 P18054 1/20 0.48
CNR1 P21554 1/20 0.48
PTGS1 P23219 1/20 0.48
PTGS2 P35354 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23876702 0.81 NOX1 (0.54) NOX1GAAMAPTBCHEACHE
SCHEMBL29824891 0.81 MAOA (0.54) NOX1BCHEACHEMAOAMEN1
SCHEMBL17951856 0.81 GAA (0.50) NOX1GAAMAPTBCHEACHE
SCHEMBL14244233 0.81 MAOA (0.54) NOX1BCHEACHEMAOAMEN1
SCHEMBL23876389 0.81 CYP2D6 (0.46) NOX1GAAMAPTBCHEACHE
SCHEMBL2488772 0.73 MAOA (0.43) NOX1BCHEACHEMAOAMEN1
SCHEMBL23876383 0.71 ALOX5 (0.52) GAAMAPTSMN1; SMN2NPSR1SIGMAR1
SCHEMBL12281545 0.71 MAOA (0.41) NOX1BCHEACHEMAOAMEN1
SCHEMBL24894049 0.70 GNG2 (0.41) GAAMAPTBCHEMEN1CYP1A2
SCHEMBL24894034 0.70 GAA (0.44) GAAMAPTMAOAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023284486-A1 TETRADENTATE CYCLOMETAL PLATINUM(II) AND PALLADIUM(II) COMPLEX LUMINESCENT MATERIAL CONTAINING QUINOLINE STRUCTURAL UNIT AND APPLICATION THEREOF 浙江工业大学 2023-01-19 WO disclosed