Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2759754 | 0.89 | CYP1A2 (0.33) | HDAC3HDAC1HDAC2HDAC6TACR1 | |
| SCHEMBL2759756 | 0.87 | ACACB (0.35) | — | |
| SCHEMBL37090 | 0.81 | ACACB (0.38) | HDAC3HDAC1HDAC2HDAC6TACR1 | |
| SCHEMBL2759750 | 0.81 | CYP1A2 (0.33) | TACR1 | |
| SCHEMBL13288536 | 0.80 | KMT2A (0.35) | ELANE | |
| SCHEMBL2759786 | 0.80 | HTR2A (0.31) | — | |
| SCHEMBL2759757 | 0.79 | HTT (0.33) | — | |
| SCHEMBL2759799 | 0.77 | ACACB (0.41) | ELANE | |
| SCHEMBL13103226 | 0.77 | ACACB (0.38) | — | |
| SCHEMBL1955260 | 0.76 | CYP1A2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2352375-B1 | HERBICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-03-25 | — | — | EP | disclosed |
| EP-2352375-B1 | HERBICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-03-25 | — | — | EP | disclosed |
| US-8722578-B2 | Spiroheterocyclic pyrrolidinedione herbicidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2014-05-13 | — | — | US | disclosed |
| US-8722578-B2 | Spiroheterocyclic pyrrolidinedione herbicidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2014-05-13 | — | — | US | disclosed |
| US-8722578-B2 | Spiroheterocyclic pyrrolidinedione herbicidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2014-05-13 | — | — | US | disclosed |
| US-8415369-B2 | Spiroheterocyclic pyrrolidine dione derivatives useful as pesticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-09 | — | — | US | disclosed |
| US-8415369-B2 | Spiroheterocyclic pyrrolidine dione derivatives useful as pesticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-09 | — | — | US | disclosed |
| EP-2197844-B1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-07-25 | — | — | EP | disclosed |
| EP-2197844-B1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-07-25 | — | — | EP | disclosed |
| US-20120004105-A1 | HERBICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2012-01-05 | — | — | US | disclosed |
| US-20120004105-A1 | HERBICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2012-01-05 | — | — | US | disclosed |
| EP-2352375-A2 | HERBICIDAL COMPOSITIONS | Syngenta Participations AG (CH) | 2011-08-10 | — | — | EP | disclosed |
| US-20100311777-A1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100311777-A1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100311777-A1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-09 | — | — | US | disclosed |
| EP-2197844-A1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USEFUL AS PESTICIDES | Syngeta Participations AG (CH) | 2010-06-23 | — | — | EP | disclosed |
| WO-2010052161-A2 | HERBICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-05-14 | — | — | WO | disclosed |
| WO-2010052161-A2 | HERBICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-05-14 | — | — | WO | disclosed |
| WO-2009049851-A1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009049851-A1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004105-A1 | HERBICIDAL COMPOSITIONS | DDT, CAT, HDHD5 | HDAC3 330/4885HDAC1 643/4885HDAC2 1237/4885 |
| US-20100311777-A1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USEFUL AS PESTICIDES | DDT, PKD2, PKD1 | HDAC3 768/4885HDAC1 481/4885HDAC2 823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.