Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.30 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2759790 | 0.88 | MMP2 (0.32) | L3MBTL1 | |
| SCHEMBL2759779 | 0.86 | ADAM17 (0.32) | HTR2AHTR2CHTR2BADAM17ADAMTS5 | |
| SCHEMBL2759799 | 0.83 | ACACB (0.41) | — | |
| SCHEMBL2759785 | 0.83 | ACACB (0.31) | — | |
| SCHEMBL2759788 | 0.81 | SMURF2 (0.33) | ADAM17ADAMTS5 | |
| SCHEMBL2759742 | 0.80 | ACACB (0.36) | — | |
| SCHEMBL248941 | 0.80 | HDAC3 (0.32) | — | |
| SCHEMBL2759781 | 0.79 | ACACB (0.30) | — | |
| SCHEMBL2759797 | 0.78 | — | — | |
| SCHEMBL2759791 | 0.77 | ACACB (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2352375-B1 | HERBICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-03-25 | — | — | EP | disclosed |
| US-8722578-B2 | Spiroheterocyclic pyrrolidinedione herbicidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2014-05-13 | — | — | US | disclosed |
| US-8722578-B2 | Spiroheterocyclic pyrrolidinedione herbicidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2014-05-13 | — | — | US | disclosed |
| US-20120004105-A1 | HERBICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2012-01-05 | — | — | US | disclosed |
| US-20120004105-A1 | HERBICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004105-A1 | HERBICIDAL COMPOSITIONS | DDT, CAT, HDHD5 | HTR2A 2067/4885HTR2C 1568/4885HTR2B 1991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.