SCHEMBL2489464

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8847270	0.85	KDM4E (0.59)	KDM4EKMT2AHPGDGABRPGABRD
	SCHEMBL2483707	0.84	KDM4E (0.49)	KDM4EKMT2AHPGDGABRPGABRD
	SCHEMBL754676	0.83	KDM4E (0.41)	KDM4EKMT2AHPGDHSD17B10MAPT
	SCHEMBL752435	0.78	HPGD (0.35)	KDM4EKMT2AHPGDNNMT
	SCHEMBL1554576	0.76	LMNA (0.47)	KDM4EHPGDGABRPGABRDGABRA1
	SCHEMBL3554940	0.74	KDM4E (0.46)	KDM4EKMT2AHPGDHSD17B10MAPT
	SCHEMBL5717561	0.73	LMNA (0.52)	KDM4EMAPTPOLBALDH1A1SMN1; SMN2
	SCHEMBL1505827	0.72	TDP1 (0.61)	KDM4EHPGDTDP1HSD17B10MAPT
	SCHEMBL4763537	0.72	HPGD (0.54)	KDM4EKMT2AHPGDGABRPGABRD
	SCHEMBL21819468	0.72	SMN1; SMN2 (0.45)	KDM4EKMT2AHPGDGABRPGABRD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.