SCHEMBL1505827

SCHEMBL1505827

COc1c(C(=O)O)ccc(C(=O)O)c1OC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.61
MAPT P10636 1/20 0.61
ALDH1A1 P00352 5/20 0.50
HSD17B10 Q99714 3/20 0.50
POLB P06746 1/20 0.50
CYP1A2 P05177 1/20 0.50
KDM4E B2RXH2 3/20 0.48
HPGD P15428 2/20 0.45
HTT P42858 1/20 0.45
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
MAPK1 P28482 1/20 0.44
ALOX15 P16050 1/20 0.43
LCK P06239 1/20 0.43
FYN P06241 1/20 0.43
CDC25B P30305 1/20 0.43
CA12 O43570 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2202243 0.97 TDP1 (0.59) TDP1MAPTALDH1A1HSD17B10POLB
SCHEMBL11140197 0.89 TDP1 (0.52) TDP1MAPTALDH1A1HSD17B10POLB
SCHEMBL6646160 0.89 TDP1 (0.52) TDP1MAPTALDH1A1HSD17B10POLB
SCHEMBL6852883 0.89 MAPT (0.52) TDP1MAPTALDH1A1HSD17B10POLB
SCHEMBL419245 0.89 TDP1 (0.56) TDP1MAPTALDH1A1HSD17B10POLB
SCHEMBL102827 0.89 MAPT (0.72) TDP1MAPTALDH1A1KDM4EHPGD
SCHEMBL9679999 0.88 TDP1 (0.55) TDP1MAPTALDH1A1HSD17B10POLB
SCHEMBL14699894 0.87 ALDH1A1 (0.63) TDP1MAPTALDH1A1HSD17B10POLB
SCHEMBL11046315 0.87 MAPT (0.50) TDP1MAPTALDH1A1HSD17B10POLB
Hydrochloric Acid SCHEMBL5061862 0.87 MAPT (0.70) TDP1MAPTALDH1A1CYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11059942-B2 Aromatic polyesters from biosuccinic acid UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2021-07-13 US claimed
US-20200062895-A1 AROMATIC POLYESTERS FROM BIOSUCCINIC ACID UNIVERSITY OF FLORIDA RESEARCH FOUNDATION,INCORPORATED 2020-02-27 US claimed
CN-102584873-A Double rare earth metal-organic framework material for temperature detection and synthesis method thereof UNIV ZHEJIANG 2012-07-18 CN claimed
US-11059942-B2 Aromatic polyesters from biosuccinic acid UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2021-07-13 US disclosed
US-20200062895-A1 AROMATIC POLYESTERS FROM BIOSUCCINIC ACID UNIVERSITY OF FLORIDA RESEARCH FOUNDATION,INCORPORATED 2020-02-27 US disclosed
CN-108623795-A A kind of polyester, Preparation method and use based on full biomass monomer 武汉科技大学 2018-10-09 CN disclosed
CN-105152904-A Method for preparing 2,3-dihydroxyterephthalic acid (2,3-DHTA) INST PETROCHEMISTRY HEILONGJIANG ACADEMY OF SCIENCES 2015-12-16 CN disclosed
CN-102584873-B Double rare earth metal-organic framework material for temperature detection and synthesis method thereof UNIV ZHEJIANG 2015-07-15 CN disclosed
CN-102584873-A Double rare earth metal-organic framework material for temperature detection and synthesis method thereof UNIV ZHEJIANG 2012-07-18 CN disclosed
CN-102249901-A Preparation method of 2, 5-dialkoxy terephthalic acid SHANDONG NON METALLIC MATERIAL RES INST 2011-11-23 CN disclosed
CN-102211996-A Preparation method of 2, 5-dihydroxy terephthalic acid SHANDONG NON METALLIC MATERIAL RES INST 2011-10-12 CN disclosed
EP-2296171-A2 Use of metal-organic frame materials for producing microelectronic components BASF SE (DE) 2011-03-16 EP disclosed
US-20100297588-A1 DENTAL COMPOSITIONS WITH NATURAL TOOTH FLUORESCENCE AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-11-25 US disclosed
EP-2214621-A2 DENTAL COMPOSITIONS WITH NATURAL TOOTH FLUORESCENCE AND METHODS 3M Innovative Properties Company (US) 2010-08-11 EP disclosed
WO-2009058854-A2 DENTAL COMPOSITIONS WITH NATURAL TOOTH FLUORESCENCE AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-05-07 WO disclosed
EP-1094826-A1 NOVEL THERAPEUTIC AGENTS THAT MODULATE ALPHA-1A ADRENERGIC RECEPTORS Advanced Medicine, Inc. (US) 2001-05-02 EP disclosed
WO-1999064042-A1 NOVEL THERAPEUTIC AGENTS THAT MODULATE ALPHA-1A ADRENERGIC RECEPTORS ADVANCED MEDICINE, INC. (US) 1999-12-16 WO disclosed
US-5049280-A 2,3-dihydroxyterephthalamides as highly effective metal ion sequestering compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1991-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100297588-A1 DENTAL COMPOSITIONS WITH NATURAL TOOTH FLUORESCENCE AND METHODS PITHD1, DDX24, DACH1 TDP1 1898/4885MAPT 805/4885ALDH1A1 3070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.