SCHEMBL24896565

SCHEMBL24896565

CC(C)(C)[Si](C)(C)OCCn1c(C(=O)O)cc2ccnc(Cl)c21

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CCR9 P51686 8/20 0.39
NTRK1 P04629 4/20 0.37
DGAT1 O75907 3/20 0.37
MCL1 Q07820 2/20 0.36
CCR2 P41597 2/20 0.34
SYK P43405 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30220585 0.88 NOD2 (0.37) DGAT1
SCHEMBL24896363 0.84 SYK (0.42) CCR9NTRK1MCL1CCR2SYK
SCHEMBL24896371 0.77 GPR35 (0.46) CCR9MCL1CCR2
SCHEMBL24896325 0.77 DYRK1A (0.42) CCR9
SCHEMBL14565663 0.76 ALDH1A1 (0.55) NTRK1MCL1CCR2
SCHEMBL24896337 0.76 MAPT (0.38) CCR9DGAT1MCL1CCR2
SCHEMBL24896369 0.74 KDM5A (0.45)
SCHEMBL20504453 0.73 MCL1 (0.45) CCR9MCL1CCR2SYK
SCHEMBL30220602 0.71 GAA (0.42) SYK
SCHEMBL24896370 0.71 KDM4C (0.40) CCR9CCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4370207-B1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES INC (US) 2025-12-17 EP disclosed
EP-4370207-A1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS Nido Biosciences, Inc. (US) 2024-05-22 EP disclosed
US-20230039586-A1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. 2023-02-09 US disclosed
WO-2023287704-A1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. (US) 2023-01-19 WO disclosed
WO-2023287704-A1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. (US) 2023-01-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230039586-A1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 CCR9 3512/4885NTRK1 311/4885DGAT1 726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.