SCHEMBL2489697

SCHEMBL2489697

CO[Si](CCC[N+](C)(C)CCCS(=O)(=O)O)(OC)OC

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.54
BBOX1 O75936 1/20 0.34
APP P05067 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15282483 0.95 LMNA (0.50) LMNABBOX1
SCHEMBL16804318 0.95 LMNA (0.57) LMNABBOX1APP
SCHEMBL16724858 0.85 LMNA (0.38) LMNABBOX1APP
SCHEMBL4309125 0.83 APP (0.41) LMNAAPP
SCHEMBL1970826 0.83 BBOX1 (0.55) LMNABBOX1
SCHEMBL15292330 0.82 LMNA (0.36) LMNABBOX1APP
SCHEMBL2616658 0.81 APP (0.39) LMNAAPP
SCHEMBL918271 0.81 BBOX1 (0.46) LMNABBOX1APP
SCHEMBL30054204 0.80 BBOX1 (0.37) LMNABBOX1APP
Hydrochloric Acid SCHEMBL1971576 0.79 LMNA (0.73) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2379118-B1 NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING GEN ELECTRIC (US) 2017-10-18 EP claimed
US-9196405-B2 Stable iron oxide nanoparticles and method of production FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2015-11-24 US claimed
US-20140147387-A1 NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING GENERAL ELECTRIC COMPANY (US) 2014-05-29 US claimed
US-8728529-B2 Nanoparticle contrast agents for diagnostic imaging GENERAL ELECTRIC COMPANY (US) 2014-05-20 US claimed
US-8574549-B2 Nanoparticle contrast agents for diagnostic imaging GENERAL ELECTRIC COMPANY (US) 2013-11-05 US claimed
US-20130256583-A1 Stable Iron Oxide Nanoparticles and Method of Production FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2013-10-03 US claimed
US-20100166664-A1 NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING GENERAL ELECTRIC COMPANY (US) 2010-07-01 US claimed
US-20100166665-A1 NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING GENERAL ELECTRIC COMPANY (US) 2010-07-01 US claimed
US-20230341411-A1 METHOD AND KIT OF MEASURING CONCENTRATION OF ANALYTE NATIONAL CHUNG CHENG UNIVERSITY (TW) 2023-10-26 US disclosed
US-20200277660-A1 SYSTEM AND METHOD FOR DETECTION OF NUCLEIC ACIDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-09-03 US disclosed
US-10626448-B2 System and method for detection of nucleic acids ALVEO TECHNOLOGIES, INC. (US) 2020-04-21 US disclosed
US-10627358-B2 Method for detection of analytes ALVEO TECHNOLOGIES, INC. (US) 2020-04-21 US disclosed
US-10352899-B2 System and method for detection of silver ALVEO Technologies Inc. (US) 2019-07-16 US disclosed
US-20190144926-A1 SYSTEM AND METHOD FOR DETECTION OF NUCLEIC ACIDS ALVEO Technologies Inc. 2019-05-16 US disclosed
US-20100166666-A1 NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING GENERAL ELECTRIC COMPANY (US) 2010-07-01 US disclosed
US-20100166664-A1 NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING GENERAL ELECTRIC COMPANY (US) 2010-07-01 US disclosed
US-20100166665-A1 NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING GENERAL ELECTRIC COMPANY (US) 2010-07-01 US disclosed
US-20090202816-A1 STABILIZED SILICA COLLOID FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2009-08-13 US disclosed
US-20090202816-A1 STABILIZED SILICA COLLOID FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2009-08-13 US disclosed
WO-2007146680-A1 STABILIZED SILICA COLLOID FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION , INC. (US) 2007-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140147387-A1 NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING CD47, CD63, MACO1 LMNA 1475/4885BBOX1 2817/4885APP 4242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.