Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2488173 | 0.89 | HTT (0.46) | KMT2AMEN1L3MBTL1LMNAHTT | |
| SCHEMBL2489162 | 0.88 | KMT2A (0.41) | KMT2AMEN1CHRM1L3MBTL1LMNA | |
| SCHEMBL643252 | 0.83 | KMT2A (0.42) | KMT2AMEN1CHRM1L3MBTL1LMNA | |
| SCHEMBL642945 | 0.82 | CXCR3 (0.43) | KMT2AMEN1CHRM1L3MBTL1LMNA | |
| SCHEMBL643063 | 0.81 | CXCR3 (0.42) | KMT2AMEN1CHRM1L3MBTL1LMNA | |
| SCHEMBL644580 | 0.80 | KMT2A (0.42) | KMT2AMEN1CHRM1L3MBTL1LMNA | |
| SCHEMBL644809 | 0.80 | KMT2A (0.40) | KMT2AMEN1CHRM1L3MBTL1LMNA | |
| SCHEMBL3666768 | 0.77 | KMT2A (0.43) | KMT2AMEN1ALPLALPIALPG | |
| SCHEMBL2490288 | 0.74 | CACNA1H (0.43) | KMT2AL3MBTL1LMNAALDH1A1GAA | |
| SCHEMBL642958 | 0.73 | KMT2A (0.43) | KMT2AMEN1CHRM1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150530-B1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2011-10-26 | — | — | EP | claimed |