SCHEMBL248995

SCHEMBL248995

O=C(N=C=S)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.48
FABP5 Q01469 3/20 0.47
FABP7 O15540 2/20 0.47
EPHX2 P34913 1/20 0.45
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CASP3 P42574 2/20 0.40
CASP1 P29466 1/20 0.37
HTR2A P28223 1/20 0.37
MDM4 O15151 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2744229 0.86 KMT2A (0.49) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL2617526 0.85 KMT2A (0.48) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL7943600 0.83 KMT2A (0.51) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL8516375 0.82 KMT2A (0.54) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL16485222 0.80 KMT2A (0.51) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL6129269 0.80 KMT2A (0.51) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL17805715 0.80 KMT2A (0.51) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL29609169 0.78 KMT2A (0.50) KMT2AFABP5FABP7EPHX2CA1
Isothiocyanate SCHEMBL30858893 0.77 FABP5 (0.51) KMT2AFABP5FABP7EPHX2CA1
Isothiocyanate SCHEMBL29261606 0.77 FABP5 (0.51) KMT2AFABP5FABP7EPHX2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 656 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250352656-A1 SYNTHETIC CATIONIC PEPTIDOMIMETICS, THEIR DERIVATIVES AND PREPARATION THEREOF ALONG WITH COMPOSITIONS FOR VARIOUS MEDICAL APPLICATIONS PEPTOMER THERAPEUTICS PRIVATE LTD (IN) 2025-11-20 US claimed
EP-4525827-A1 SYNTHETIC CATIONIC PEPTIDOMIMETICS, THEIR DERIVATIVES AND PREPARATION THEREOF ALONG WITH COMPOSITIONS FOR VARIOUS MEDICAL APPLICATIONS Peptomer Therapeutics Private Limited (IN) 2025-03-26 EP claimed
WO-2023209728-A1 SYNTHETIC CATIONIC PEPTIDOMIMETICS, THEIR DERIVATIVES AND PREPARATION THEREOF ALONG WITH COMPOSITIONS FOR VARIOUS MEDICAL APPLICATIONS PEPTOMER THERAPEUTICS PRIVATE LIMITED (IN) 2023-11-02 WO claimed
US-20020049320-A1 6-amino-2,4-dioxo-3,4-dihydro-1,3,5-triazine derivatives and methods for the solid phase synthesis thereof AMERICAN CYANAMID COMPANY 2002-04-25 US claimed
EP-4003988-B1 3,6-DIAMINO-PYRIDAZIN-3-YL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS SERVIER LAB (FR) 2026-05-20 EP disclosed
EP-4735453-A1 KRAS MODULATING COMPOUNDS GILEAD SCIENCES, INC. (US) 2026-05-06 EP disclosed
EP-4735445-A1 KRAS MODULATING COMPOUNDS GILEAD SCIENCES, INC. (US) 2026-05-06 EP disclosed
EP-4709371-A1 SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT Merck Sharp & Dohme LLC (US) 2026-03-18 EP disclosed
EP-4704854-A2 PRMT INHIBITOR COMPOUNDS AND THE USES THEREOF Purdue Research Foundation (US) 2026-03-11 EP disclosed
EP-4695260-A1 KRAS MODULATING COMPOUNDS GILEAD SCIENCES, INC. (US) 2026-02-18 EP disclosed
US-20250352656-A1 SYNTHETIC CATIONIC PEPTIDOMIMETICS, THEIR DERIVATIVES AND PREPARATION THEREOF ALONG WITH COMPOSITIONS FOR VARIOUS MEDICAL APPLICATIONS PEPTOMER THERAPEUTICS PRIVATE LTD (IN) 2025-11-20 US disclosed
US-12440706-B2 Conjugated chemical inducers of degradation and methods of use GENENTECH, INC. (US) 2025-10-14 US disclosed
WO-2002004407-A2 7-SUBSTITUTED TETRACYCLINE COMPOUNDS TRUSTEES OF TUFTS COLLEGE (US) 2002-01-17 WO disclosed
WO-2002004406-A2 9-SUBSTITUTED MINOCYCLINE COMPOUNDS TRUSTEES OF TUFTS COLLEGE (US) 2002-01-17 WO disclosed
WO-2001087882-A2 SUBSTITUTED PYRROLOPYRIDINONE DERIVATIVES USEFUL AS PHOSPHODIESTERASE INHIBITORS ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2001-11-22 WO disclosed
WO-2001087038-A2 β-CARBOLINE DERIVATIVES USEFUL AS INHIBITORS OF PHOSPHODIESTERASE ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2001-11-22 WO disclosed
WO-2001083478-A2 HYDANTOIN-CONTAINING GLUCOKINASE ACTIVATORS F. HOFFMANN-LA ROCHE AG (CH) 2001-11-08 WO disclosed
WO-2001074761-A1 7-AND 9-CARBAMATE, UREA, THIOUREA, THIOCARBAMATE, AND HETEROARYL-AMINO SUBSTITUTED TETRACYCLINE COMPOUNDS TRUSTEES OF TUFTS COLLEGE (US) 2001-10-11 WO disclosed
WO-2001019829-A2 PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS BASF AKTIENGESELLSCHAFT (DE) 2001-03-22 WO disclosed
WO-2001017995-A1 TYROSINE KINASE INHIBITORS MERCK & CO., INC. (US) 2001-03-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020049320-A1 6-amino-2,4-dioxo-3,4-dihydro-1,3,5-triazine derivatives and methods for the solid phase synthesis thereof DAZAP1, DCUN1D5, DHX15 KMT2A 2900/4885FABP5 1912/4885FABP7 3661/4885
US-20250352656-A1 SYNTHETIC CATIONIC PEPTIDOMIMETICS, THEIR DERIVATIVES AND PREPARATION THEREOF ALONG WITH COMPOSITIONS FOR VARIOUS MEDICAL APPLICATIONS NOD2, NGLY1, CGAS KMT2A 4744/4885FABP5 3490/4885FABP7 3364/4885
US-12440706-B2 Conjugated chemical inducers of degradation and methods of use ADRM1, SSB, FCER2 KMT2A 4147/4885FABP5 912/4885FABP7 1875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.