Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14037359 | 0.81 | KDM4E (0.36) | KDM4EALDH1A1MAPK1SMN1; SMN2PAX8 | |
| SCHEMBL24724553 | 0.77 | TUBB1 (0.35) | KDM4EALDH1A1MAPK1SMN1; SMN2PAX8 | |
| SCHEMBL30570727 | 0.77 | TUBB1 (0.35) | KDM4EALDH1A1MAPK1SMN1; SMN2PAX8 | |
| SCHEMBL30259592 | 0.76 | MEP1B (0.37) | KDM4EALDH1A1MAPK1SMN1; SMN2MCL1 | |
| SCHEMBL23967512 | 0.76 | TUBB1 (0.42) | KDM4EALDH1A1MAPK1SMN1; SMN2PAX8 | |
| SCHEMBL3832480 | 0.76 | MEP1B (0.37) | KDM4EALDH1A1MAPK1SMN1; SMN2MCL1 | |
| SCHEMBL31013129 | 0.75 | ALDH1A1 (0.43) | KDM4EALDH1A1MAPK1SMN1; SMN2MCL1 | |
| SCHEMBL881613 | 0.75 | ALDH1A1 (0.43) | KDM4EALDH1A1MAPK1SMN1; SMN2MCL1 | |
| SCHEMBL14092120 | 0.74 | ALOX5AP (0.39) | KDM4EALDH1A1MAPK1SMN1; SMN2PAX8 | |
| SCHEMBL525262 | 0.74 | ALDH1A1 (0.42) | KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284869-A1 | SULFUR/PHOSPHORUS-CONTAINING ARYL COMPOUND AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2023-01-19 | — | — | WO | disclosed |