Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL881613 | 1.00 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPK1SMN1; SMN2MCL1 | |
| SCHEMBL3751809 | 0.87 | CYP1A1 (0.40) | ALDH1A1KDM4ESMN1; SMN2CA9CA2 | |
| SCHEMBL31571429 | 0.87 | CYP1A1 (0.40) | ALDH1A1KDM4ESMN1; SMN2CA9CA2 | |
| SCHEMBL3951547 | 0.84 | CA2 (0.43) | ALDH1A1KDM4EMAPK1SMN1; SMN2MCL1 | |
| SCHEMBL3648629 | 0.81 | SMN1; SMN2 (0.46) | ALDH1A1KDM4EMAPK1SMN1; SMN2MCL1 | |
| SCHEMBL881615 | 0.78 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPK1SMN1; SMN2TPMT | |
| SCHEMBL9376529 | 0.78 | SMN1; SMN2 (0.44) | ALDH1A1KDM4EMAPK1SMN1; SMN2CA9 | |
| SCHEMBL31443878 | 0.78 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPK1SMN1; SMN2TPMT | |
| SCHEMBL7708761 | 0.76 | NNMT (0.43) | ALDH1A1KDM4ECA2CA1TPMT | |
| SCHEMBL24899657 | 0.75 | KDM4E (0.31) | ALDH1A1KDM4EMAPK1SMN1; SMN2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096856-A1 | COVALENT CEREBLON LIGANDS | C4 THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| CN-112203653-B | Compounds for the treatment of huntington's disease | PTC医疗公司 | 2024-08-16 | — | — | CN | disclosed |