Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24899760 | 0.83 | SMN1; SMN2 (0.35) | ALDH1A1LMNASMN1; SMN2MAPTKDM4E | |
| SCHEMBL24899755 | 0.76 | SMN1; SMN2 (0.37) | ALDH1A1LMNASMN1; SMN2MAPTKDM4E | |
| SCHEMBL24899826 | 0.75 | SMN1; SMN2 (0.39) | ALDH1A1LMNASMN1; SMN2MAPTKDM4E | |
| SCHEMBL9881056 | 0.73 | ENPP2 (0.41) | KDM4E | |
| SCHEMBL24899641 | 0.72 | — | — | |
| SCHEMBL24899723 | 0.67 | DRD1 (0.37) | SMN1; SMN2MAPTKDM4E | |
| SCHEMBL24899758 | 0.67 | MAPT (0.34) | ALDH1A1LMNASMN1; SMN2MAPTKDM4E | |
| SCHEMBL24899728 | 0.66 | CDK1 (0.35) | SMN1; SMN2MAPTKDM4E | |
| SCHEMBL24899756 | 0.65 | CA2 (0.44) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL24899887 | 0.65 | HSD17B10 (0.49) | ALDH1A1LMNASMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284869-A1 | SULFUR/PHOSPHORUS-CONTAINING ARYL COMPOUND AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2023-01-19 | — | — | WO | disclosed |