SCHEMBL68818

SCHEMBL68818

COC(=O)c1ccc(-c2ccccc2C(=O)OC)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 5/20 0.73
SLC6A4 P31645 3/20 0.73
SLC6A2 P23975 1/20 0.64
EGFR P00533 1/20 0.58
TSHR P16473 2/20 0.57
PTPN1 P18031 2/20 0.55
PTPRC P08575 1/20 0.55
PTPRF P10586 1/20 0.55
CDC25B P30305 1/20 0.55
ROCK2 O75116 1/20 0.52
CSF1R P07333 1/20 0.52
KDR P35968 1/20 0.52
FLT3 P36888 1/20 0.52
GSK3A P49840 1/20 0.52
GSK3B P49841 1/20 0.52
CDK5 Q00535 1/20 0.52
ROCK1 Q13464 1/20 0.52
SLK Q9H2G2 1/20 0.52
IRAK4 Q9NWZ3 1/20 0.52
ALDH1A1 P00352 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6713222 0.90 SLC6A3 (0.59) SLC6A3SLC6A4SLC6A2EGFRTSHR
SCHEMBL5500070 0.90 SLC6A3 (0.69) SLC6A3SLC6A4SLC6A2EGFRTSHR
SCHEMBL708402 0.90 SLC6A3 (0.69) SLC6A3SLC6A4SLC6A2EGFRTSHR
SCHEMBL28486252 0.88 SLC6A3 (0.57) SLC6A3SLC6A4SLC6A2EGFRTSHR
SCHEMBL31318316 0.87 SLC6A3 (0.78) SLC6A3SLC6A4SLC6A2EGFRTSHR
SCHEMBL1775832 0.87 SLC6A3 (0.74) SLC6A3SLC6A4SLC6A2TSHRROCK2
SCHEMBL27843639 0.87 SLC6A3 (0.74) SLC6A3SLC6A4SLC6A2TSHRPTPRC
SCHEMBL6803271 0.87 SLC6A3 (0.65) SLC6A3SLC6A4SLC6A2EGFRTSHR
SCHEMBL8923988 0.86 SLC6A3 (0.73) SLC6A3SLC6A4SLC6A2TSHRROCK2
SCHEMBL249 0.86 SLC6A3 (0.73) SLC6A3SLC6A4SLC6A2TSHRROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 SLC6A3 3908/4885SLC6A4 2652/4885SLC6A2 3474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.