Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.73 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | CSF1R | P07333 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.52 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.52 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31318316 | 0.87 | SLC6A3 (0.78) | SLC6A3SLC6A4SLC6A2LMNATSHR | |
| SCHEMBL27843639 | 0.87 | SLC6A3 (0.74) | SLC6A3SLC6A4SLC6A2LMNATSHR | |
| SCHEMBL1775832 | 0.87 | SLC6A3 (0.74) | SLC6A3SLC6A4SLC6A2LMNATSHR | |
| Dimethyl Phthalate SCHEMBL28245676 | 0.87 | TSHR (0.62) | SLC6A3SLC6A4SLC6A2LMNATSHR | |
| SCHEMBL68818 | 0.86 | SLC6A3 (0.73) | SLC6A3SLC6A4SLC6A2LMNATSHR | |
| SCHEMBL249 | 0.86 | SLC6A3 (0.73) | SLC6A3SLC6A4SLC6A2LMNATSHR | |
| Bicarbonate SCHEMBL27467504 | 0.85 | SLC6A3 (0.72) | SLC6A3SLC6A4SLC6A2LMNATSHR | |
| Phosphine SCHEMBL11469830 | 0.85 | SLC6A3 (0.72) | SLC6A3SLC6A4SLC6A2LMNATSHR | |
| SCHEMBL5700615 | 0.85 | SLC6A3 (0.72) | SLC6A3SLC6A4SLC6A2LMNATSHR | |
| SCHEMBL8064603 | 0.85 | SLC6A3 (0.54) | SLC6A3SLC6A4SLC6A2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111377846-B | Piperazine benzamide derivative and application thereof | 江苏恩华药业股份有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-111377846-A | Piperazine benzamide derivative and application thereof | 江苏恩华药业股份有限公司 | 2020-07-07 | — | — | CN | disclosed |
| US-5658493-A | Ferroelectric liquid crystals for nonlinear optics applications | UNIVERSITY RESEARCH CORPORATION (US) | 1997-08-19 | — | — | US | disclosed |
| US-5637256-A | Ferroelectric liquid crystals for nonlinear optics applications | UNIVERSITY RESEARCH CORPORATION (US) | 1997-06-10 | — | — | US | disclosed |
| WO-1996037511-A1 | CYCLIC PEPTIDES ANTIFUNGAL AGENTS | ELI LILLY AND COMPANY (US) | 1996-11-28 | — | — | WO | disclosed |
| US-5543078-A | A CHIRAL NONRACEMIC COMPOUND | UNIVERSITY RESEARCH CORPORATION (US) | 1996-08-06 | — | — | US | disclosed |
| US-5298593-A | Polymerization of ester monomer, aromatic dicarboxylic acid, and oxyaromatic carboxylic acid | MITSUBISHI PETROCHEMICAL COMPANY, LTD. (JP) | 1994-03-29 | — | — | US | disclosed |
| US-5270322-A | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1993-12-14 | — | — | US | disclosed |
| EP-0555825-A1 | Imidazo(1,2-a)pyridines as angiotensin-II-antagonists | Dr. Karl Thomae GmbH (DE) | 1993-08-18 | — | — | EP | disclosed |
| EP-0520428-A2 | Method of producing thermotropic liquid crystalline polyester | MITSUBISHI CHEMICAL CORPORATION (JP) | 1992-12-30 | — | — | EP | disclosed |
| WO-1992020058-A2 | FERROELECTRIC LIQUID CRYSTALS FOR NONLINEAR OPTICS APPLICATIONS | UNIVERSITY RESEARCH CORPORATION (US) | 1992-11-12 | — | — | WO | disclosed |