Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 11/20 | 0.48 |
| ▸ | CDK12 | Q9NYV4 | 11/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 10/20 | 0.48 |
| ▸ | CDK2 | P24941 | 10/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 9/20 | 0.48 |
| ▸ | CDK9 | P50750 | 9/20 | 0.48 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.45 |
| ▸ | CDK7 | P50613 | 8/20 | 0.43 |
| ▸ | CCNH | P51946 | 8/20 | 0.43 |
| ▸ | MNAT1 | P51948 | 7/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30957595 | 1.00 | CCNK (0.48) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL30957590 | 0.90 | TDO2 (0.47) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL24900493 | 0.90 | TDO2 (0.47) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL29993829 | 0.84 | CDK7 (0.54) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL517413 | 0.84 | CDK7 (0.54) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL21178391 | 0.81 | CCNK (0.47) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL21184587 | 0.80 | CCNK (0.42) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL21178668 | 0.80 | CLK1 (0.50) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL21629046 | 0.80 | CCNK (0.44) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL30554768 | 0.80 | CCNK (0.44) | CCNKCDK12CCNE1CDK2CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287783-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | ACEA Therapeutics, Inc. (US) | 2023-01-19 | — | — | WO | disclosed |